I-Medium-Chain Triglycerides (MCT) Pharmaceutical Grade | I-Lipophilic Solvent kunye ne-Drug Carrier yomlomo/engaphandle/enokutofwa | USP/EP/ChP

I-Medium-Chain Triglycerides (MCT) yethu sisithako samayeza esicocekileyo kakhulu esenziwe ngama-triglycerides e-caprylic (C8) kunye ne-capric (C10) fatty acids, ephuma kwi-coconut kunye ne-palm kernel oils.Ibonakala ngathi lulwelo olunamafutha olucacileyo, olungenambala ukuya kolutyheli kancinci, olunevumba elingathathi cala kunye nencasa engathathi calaI-MCT isebenza njengesinyibilikisi esibalaseleyo samayeza anciphisa i-lipophilic, isithwali samayeza sokuphucula ukufumaneka kwamachiza, isithomalalisi seefomyula ezisetyenziswa esikhumbeni, kunye nesiphuculisi sokungena kwesikhumba.Inika uzinzo oluphezulu lwe-oxidative, ukufunxwa ngokukhawuleza (ukujikeleza ngqo kwe-portal ngaphandle kwe-bile salts), kunye nokuhambelana okuhle kakhulu nee-API kunye nezinye izinto ezincedisayo.. Ihambelana ne-USP-NF, EP, JP, kunye ne-ChP pharmacopoeias kunye ne-CDE registration F20220000316Ifanelekile kwizisombululo/iikhaphu zomlomo, iikhrimu/izithambiso zangaphandle, isondlo se-parenteral, kunye neenkqubo zokuhambisa amayeza ezizixuba ngokwazo (ii-SEDDS).

Qhagamshelana nathi

Iinkcukacha zeMveliso

IiTriglycerides zeChain Medium-Chain zePharmaceutical Grade (MCT)

Isishwankathelo seMveliso

I-Medium-Chain Triglycerides (MCT) sisithako esisebenzayo samayeza esiqulathe umxube we-triglycerides ye-saturated fatty acids, ikakhulu i-caprylic acid (C8H16O2, i-octanoic acid) kunye ne-capric acid (C10H20O2, i-decanoic acid)Ezi triglycerides zifunyanwa kwioyile esisigxina ethathwe kwinxalenye eqinileyo neyomileyo ye-endosperm yekhokhonathi (iCocos nucifera L.) okanye kwi-endosperm eyomileyo ye-oil palm (i-Elaeis guineensis Jacq.)Ii-fatty acids zahlulwa kwi-fat oil kwaye ziphinde zifakwe i-glycerol ukuvelisa imveliso yokugqibela..

Ubume beMveliso:

Igama leKhemikhali:IiTriglycerides zeChain ephakathi / iCaprylic/iCapric Triglyceride
Inombolo ye-CAS:73398-61-5 (kwakhona 85409-09-2 okanye 538-24-9)
Inombolo yoBhaliso lwe-CDE:F20220000316
Ukuthobela i-Pharmacopoeia:I-ChP (CP2020), i-USP-NF (iiTriglycerides zeChain ephakathi), i-EP (iiTriglycerides, iChain ephakathi), i-JP (iitriglycerides zechain ephakathi)
Izithethantonye:Ioyile ye-MCT, iCaprylic/Capric Triglyceride, iiGlycerides ezixutyiweyo ze-decanoyl kunye ne-octanoyl, iMiglyol® 812 elinganayo, iLabrafac™ CC elinganayo
Inkangeleko:Ulwelo olunamafutha olungenambala ukuya kolutyheli kancinci, alunavumba kwaye alunancasa
Indawo yokuqandisa:Malunga ne-0°C

Iimpawu eziphambili kunye neenzuzo

1. Iimpawu zeSolvent eziBalaseleyo

Isinyibilikisi esigqibeleleyo samayeza e-lipophilic kunye nee-APIs ezinganyibilikiyo emanzini kakuhle
Iphucula ukunyibilika kunye nokuzinzisa iikhompawundi ze-lipophilic
Iphucula ukufumaneka kwamachiza eKlasi yesiBini kunye neKlasi yesiIV (uhlelo lweBCS)

2. Ukufunxwa Okukhawulezileyo kunye neMetabolism

Ifunxwa ngqo kwi-portal circulation ngaphandle kwesidingo se-bile salts okanye ii-enzymes ze-pancreatic
Iguqulwa ngokukhawuleza ukuze inike amandla ngokukhawuleza
Ukuhanjiswa kwe-API ngokukhawuleza kwindlela yokujikeleza kwegazi, okunokuphucula ukuqala kokusebenza

3. Iprofayili yozinzo oluhle kakhulu

Ukumelana okuphezulu ne-oxidation (ixabiso le-iodine ≤1.0)
Ukungakwazi ukusebenza kakuhle koxinzelelo lobushushu kunye noxinzelelo lwe-oxidative
Igcina uzinzo kunye nobomi beshelufu beendlela zokwenza amayeza
Izinzile kumanqanaba obushushu okugcina ahlukeneyo (≤25°C iyacetyiswa)

4. Iimpawu Eziphezulu Zomzimba

Ukuxinana:~30 mPa·s kwi-20°C (i-viscosity ephantsi ukuze kube lula ukuyiphatha)
Ubunzima obuthile:0.93-0.96 kwi-20°C
Isalathisi sokuKhangela:1.440-1.452 kwi-20°C
Ubuninzi obuphantsi obufanelekileyo kwiifom zedosi ezingamanzi kunye neziqinileyo

5. Ukuhambelana Okugqwesileyo

Iyahambelana noluhlu olubanzi lwee-API kunye nezinto ezincedisayo kwiyeza
Ingafakwa ngokulula kwiifomyula ezahlukeneyo ngaphandle kweengxaki zokuhambelana
Ivumba nencasa engathathi cala – ilungele ukusetyenziswa ngomlomo apho ukuncasa kubalulekile khona

6. Iprofayili yoLawulo noKhuseleko