I-Croscarmellose Sodium Superdisintegrant yeeThebhulethi zamayeza | Ukudumba okukhawulezayo, iNqanaba lokusetyenziswa eliphantsi yi-0.5-5% | I-USP/EP/JP Iyahambelana

I-Croscarmellose Sodium yethu yi-superdisintegrant ecocekileyo kakhulu eyenzelwe iifom zomthamo oqinileyo womlomo kuquka iipilisi, iikhaphu, kunye neegranules. Yi-sodium carboxymethylcellulose edibeneyo ngaphakathi enganyibiliki emanzini kodwa ikhula ngokukhawuleza ukuya kuthi ga kwi-4-8 ivolumu yayo yokuqala xa idibana ne-aqueous media.Esi sakhiwo sikhethekileyo sinee-fiber sinika amandla amahle okucoca amanzi kunye nokusebenza kakuhle kwe-capillary, nto leyo ekhokelela ekuqhekekeni okuphezulu kwethebhulethi kunye nokuphuculwa kokunyibilika kwamayeza.. Ihambelana ne-USP-NF, EP, JP, kunye ne-ChP pharmacopoeias kunye ne-CDE registration F20209990136Inqanaba eliqhelekileyo lokusetyenziswa: 0.5-5.0% w/w (2% yoxinzelelo oluthe ngqo, 3% yomxube omanzi)Ifanelekile ukucinezelwa ngokuthe ngqo, ukugalelwa kwe-granulation emanzi (ngaphakathi okanye ngaphandle kwe-granular), ukuxinana kwe-roller, kunye ne-capsule formulations

Qhagamshelana nathi

Iinkcukacha zeMveliso

I-Croscarmellose Sodium yeKlasi yaMayeza (i-CCS)

Isishwankathelo seMveliso

ICroscarmellose Sodium yi-sodium carboxymethylcellulose edityaniswe ngaphakathi, eyenzelwe ngokukodwa ukusetyenziswa njenge-superdisintegrant kwi-pharmaceutical formulations Ngokungafaniyo nezinto eziqhekekayo eziqhelekileyo, inika iipropati eziqhekekayo ezibalaseleyo xa zinomlinganiselo ophantsi, iqinisekisa ukuqhekeka ngokukhawuleza kweepilisi kunye nokuphuculwa kokunyibilika kwamayeza ukuze kubekho ukufumaneka okuphuculweyo kwezinto eziphilayo..

Ubume beMveliso:

Igama leKhemikhali:I-Crosscarmellose Sodium
Inombolo ye-CAS:74811-65-7
Inombolo yoBhaliso lwe-CDE:F20209990136
Ukuthobela i-Pharmacopoeia:I-ChP, i-USP-NF, i-EP, i-JP, i-BP
Inombolo ye-EC:629-739-2
Izithethantonye:I-Carboxymethylcellulose edityanisiweyo ne-Croscarmellose, i-CCNa, i-Sodium Croscarmellose, i-E468

Iimpawu eziphambili kunye neenzuzo

1. Indlela Ebalaseleyo Yokuqhekeka

Ukuqhekeka kwezenzo ezimbini:Idibanisa isenzo se-capillary (wicking) kunye nokudumba okukhawulezayo
Iyanda ukuyaIphindaphindwe ka-4-8 umthamo wayo wokuqalaxa udibana namanzi
Ulwakhiwo olunemicu lubonelela ngezakhono ezibalaseleyo zokufunxa amanzi
Yenza ulwandiso loomatshini oluqhekeza ngokukhawuleza iipilisi

2. Inqanaba lokusetyenziswa eliphantsi – Ukusebenza kakuhle okuphezulu

Isebenza kakuhle xa kugxilwe kumanqanaba aphantsi njenge0.5-5.0% w/w
Ukusetyenziswa okuqhelekileyo: 2% yokucinezela ngokuthe ngqo, 3% yokubumbana okumanzi
Isisombululo esingabizi kakhulu sokuphuhlisa ifomula

3. Ukuguquguquka kweFomu

Ifanelekile kuzo zonke iinkqubo zokufaka iipilisi: ucinezelo oluthe ngqo, i-granulation emanzi, ucinezelo lwe-roller
Kwi-granulation emanzi, ingasetyenziswa ngaphakathi kwe-granularly, extra-granularly, okanye yahlulwe phakathi kwezigaba zombini
Iyahambelana neefomyula ze-capsule (ukusetyenziswa kwe-10-25%)

4. Iipropati Ezintle Zomzimba

Inkangeleko:Umhlophe ukuya komhlophe, umgubo ohamba ngokukhululekileyo
Inqanaba lokutshintsha:0.60 – 0.85
Umthamo Wokuhlalisa:10.0 – 30.0 ml
isisombululo se-pH (1%):5.0 – 7.0
Ilahleko xa komiswa:≤10.0%
Intsalela xa kutsha:14.0% – 28.0%
Izinto Ezinyibilikayo Ngamanzi:≤10.0%
Iintsimbi Ezinzima:≤10 ppm

5. Ukuhambelana kwe-API kunye nozinzo

Ngabaayinazo iiperoxide– iqinisekisa uzinzo olungcono kwii-API ezibuthathaka kwi-oxidation
Akukho mpembelelo imbi kubunzima bethebhulethi okanye ukugungqa kwayo
Ukusebenza kokuqhekeka kuhlala kufana ngokuhamba kwexesha
Ayisiyo-GMO, ayina-allergen